Last data update: May 13, 2024. (Total: 46773 publications since 2009)
Records 1-2 (of 2 Records) |
Query Trace: Knutson K[original query] |
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Notes from the field: Increase in coccidioidomycosis - California, 2016
Cooksey GS , Nguyen A , Knutson K , Tabnak F , Benedict K , McCotter O , Jain S , Vugia D . MMWR Morb Mortal Wkly Rep 2017 66 (31) 833-834 Coccidioidomycosis, or Valley Fever, is an infectious disease caused by inhalation of Coccidioides spp. spores. This soil-dwelling fungus is endemic in the southwestern United States, with most (97%) U.S. cases reported from Arizona and California. Following an incubation period of 1-3 weeks, symptomatic patients most often experience self-limited, influenza-like symptoms, but coccidioidomycosis also can lead to severe pulmonary disease and to rare cases of disseminated disease, including meningitis. Those at increased risk for severe disease include persons of African or Filipino descent, pregnant women, adults in older age groups, and persons with weakened immune systems. In 2016, a large increase in coccidioidomycosis incidence was observed in California compared with previous years. Using data reported by health care providers and laboratories via local health departments to the California Department of Public Health as of May 9, 2017, incidence rates were calculated by estimated year of illness onset as the number of confirmed coccidioidomycosis cases per 100,000 population. Estimated year of illness onset was extracted from the closest date to the time when symptoms first appeared for each patient. From 1995, when coccidioidomycosis became an individually reportable disease in California, to 2009, annual incidence rates ranged from 1.9 to 8.4 per 100,000, followed by a substantial increase to 11.9 per 100,000 in 2010 and a peak of 13.8 per 100,000 in 2011 (Figure). Annual rates decreased during 2012-2014, but increased in 2016 to 13.7 per 100,000, with 5,372 reported cases, the highest annual number of cases in California recorded to date. |
Miniature differential mobility analyzer for compact field-portable spectrometers
Qi C , Kulkarni P . Aerosol Sci Technol 2016 50 (11) 1145-1154 A low-flow miniature differential mobility analyzer (mDMA) has been developed for compact field-portable mobility spectrometers to classify the submicrometer aerosol. The mDMA was designed for an ultra-low aerosol flow rate of 0.05 L/min. At a sheath flow rate of 0.2 L/min, the mDMA's upper size limit was estimated to be about 921 nm. The mDMA has a classification zone of 2.54 cm long, an outer diameter of 2.54 cm, and an inner diameter of 1.778 cm. The design allows low-cost fabrication and easy assembly. Tandem DMA measurements were carried out to evaluate the performance of the mDMA. Its transfer function was described using Stolzenburg's model. The experimentally measured transfer function shows close agreement with the theory. The transmission efficiency was comparable to that of the Knutson–Whitby DMA for particles in the range of 10–1000 nm. The mobility resolution was comparable to that of the TSI 3085 nanoDMA at the same aerosol flow rate. The design features and performance of the mDMA make it suitable for compact field portable mobility size spectrometers for measurement of nanoparticles and submicrometer aerosol. © 2016 This article not subject to U.S. copyright law |
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